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Dr. Mauriello's long interest in blepharospasm began in the early 1980's. He was part of the original National Institute of Health's study entitled, Botulinum Toxin in the Treatment of Benign Essential Blepharospasm. This multicenter center was under the direction of Alan Scott, MD, Principal Investigator from Pacific Medical Center in San Francisco (1983-1989).

Dr. Mauriello was honored to be selected a consultant to the Committee of Ophthalmic Procedures Assessment, American Academy of Ophthalmology 1985-89. This committee evaluated the effectiveness of botulinum toxin, type A, during its experimental research development.

Dr. Mauriello currently serves as a Reviewer to the American Academy of Neurology Therapeutics Assessment Committee and its Subcommittee Assessment of BotulinumToxin Therapy.

He was invited to the speaker's Bureau of Allergan Pharmaceutical (Botox) , Irvine, California in 1997 and served on the Board of Medical Advisors of the local Northern New Jersey Blepharospasm Foundation in Summit, NJ from 1985-88.

Dr. Mauriello's interest in facial dyskinesias is highlighted by the series of original publications, book chapters, and presentations he has made since 1985.

ORIGINAL REFEREED PUBLISHED SCIENTIFIC ARTICLES BY DR. MAURIELLO

1. Mauriello JA: Blepharospasm, Meige syndrome, and hemi-facial spasm: treatment with botulinum toxin. Neurology 35:1499-1500, 1985.

2. Mauriello JA, Coniaris H, Haupt E: Use of botulinum toxin in the treatment of one hundred patients with facial dyskinesias. Ophthalmol 94:976-979, 1987.

3. Mauriello JA, Aljian JA: Natural history of the treatment of facial dyskinesias with botulinum toxin: A study of 50 consecutive patients over 7 years. Brit J Ophthalmol 75:737-739, 1991.

4. Mauriello JA, Dhillon S, Leone T, Pakeman B, Mostafavi R, Yepez MC. Treatment profile of 239 patients with blepharospasm and Meige syndrome over 11 years. Brit J Ophthalmol 80:1073-1075, 1996.

5. Mauriello JA, Leone T, Dhillon S, Pakeman B, Mostafavi R, Yepez. Treatment choices of 119 patients with hemifacial spasm over 11years. Clinical Neurology and Neurosurgery 98: 213-216, 1996.

6. Mauriello JA, Carbonaro P, Dhillon S, Leone T, Franklin M. Drug-associated facial dyskinesias--a study of 238 patients Neuro-Ophthalmology 18:153-7,1998.

7. Mauriello JA, Keswani R, Franklin MN. Long-term enhancement of botulinum toxin injections by upper eyelid surgery in 14 patients with facial dyskinesias

Archives of Otolaryngology-Head and Neck Surgery 125: 627-631,1999.

PUBLISHED BOOKS AND CHAPTERS BY DR. MAURIELLO

Mauriello JA: Treatment of benign essential blepharospasm and hemifacial spasm: a preliminary study of 68 patients. In: Advances in Ophthalmic Plastic & Reconstructive Surgery (Volume 4), Smith B & Bosniak S (Eds); Pergammon Press, N.Y., N.Y., 1985, pp 283-289.

Mauriello JA, Wagner, RS, Mostafavi R, Frohman, L: Oculinum Therapy: its use in Neuro-ophthalmology (Treatment of Facial Dyskinesia) in Neuro- ophthalmological disorders: Diagnostic Workup and Treatment, Tusa R, Newman SA (Ed); Marcel Dekker, 1994, 451-477.

Mauriello JA. Editorial commentary: Causes and treatment of blepharospasm: botulinum toxin, limited myectomy, and pharmacologic therapy, on in Surgical management of essential blepharospasm, Patel, BCK, Anderson, RL. Chapter 8, 197-204 in Unfavorable Results of Eyelid and Lacrimal Surgery Prevention and Management. Mauriello JA (ed); Butterworth-Heinemann, Boston, Mass, 2000.

PUBLISHED ABSTRACTS, NATIONAL, REGIONAL, AND LOCAL SCIENTIFIC PRESENTATIONS

Mauriello, JA: Drug-Induced Blepharospasm, Benign Essential Blepharopasm Research Foundation and the National Institute of Neurological Disorders, Washington, DC, November 16 and 17, 2000.

Mauriello, JA: Blepharospasm and Hemifacial Spasm, Invited Speaker, International Symposium on Movement Disorders, Orlando, Florida, November 18, 1999

Mauriello JA, Keswani R, Franklin M: Enhancement of botulinum toxin injections by upper eyelid surgery including limited myectomy in the treatment of a cohort of 358 patients with facial dyskinesias. Annual Fall meeting of the American Academy of Ophthalmology, San

Francisco, California, October 29, 1997.

Mauriello JA: Update on the Treatment of Essential Blepharospasm with Botulinum Toxin. New Jersey Academy of Ophthalmology, Ophthalmic Allied Health Symposium, Long Branch, N.J., December 1,

1993.

Wagner RS, Mauriello JA: The use of Botulinum toxin for the treatment of strabismus and blepharospasm. Mediprecis 2:4-5, 1986.

Mauriello JA, Coniaris H: Use of botulinum toxin in the treatment of 100 patients with facial dyskinesias. Ophthalmology, (Suppl) 93: 1986.

Mauriello JA: Treatment of facial dyskinesias with botulinum toxin. Westchester County Medical Society, Valhalla, N.Y., April 30, 1985.

Mauriello JA: Treatment of blepharospasm with botulinum toxin. Grand Rounds, Department of Neurology, Rutgers Medical School, New Brunswick, N.J., March 23, 1985.

Mauriello JA: Blepharospasm. N.Y. Chapter of National Blepharospasm Foundation, Long Island Jewish Medical Center, N.Y., January 27, 1985.

Mauriello JA: Treatment of essential blepharospasm with botulinum toxin. New Jersey Academy of Ophthalmology, Ophthalmic Allied Health Symposium, Parsippany, N.J., October 10, 1984.

Mauriello JA: Treatment of essential Blepharospasm, Local Northern N.J. Chapter of the Blepharospasm Foundation, St. Barnabas Medical Center, Livingston, N.J., May 1984.

Mauriello JA: Treatment of essential

blepharospasm. Channel 13, PBS, WNET, "Innovations," Newark, N.J., May 3 & May 6, 1984.

Mauriello JA: Essential blepharospasm: a new treatment. New Jersey Academy of Ophthalmology, Fall 1983.